Hi,
with USB (just wire the radio to the computer, do nothing else), the computer should instantly recognize the radio as a USB HID (see Device Manager/System Settings).
Then, any Sim which supports USB inputs should recognize that 'Joystick'.
Wireless, whatever adapter used (RX2Sim or china cracker PPM2USB adapter) should also be recognized by the computer, might require a proprietary driver, and that adapter in turn should recognize VSim (PPM) or VBasic/VBar NEO w/ macrocells and output as selected (e.g. SBus).
There is not much magic in it
Cheers
Eddi
Born to fly ...
forced to work.